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Background: Simultaneous ST-segment elevation in the precordial and inferior leads is...
Study objectives: To establish a clinically relevant animal model of pulmonary metast...
A Case Report An unusual endobronchial presentation of lympho-epithelial cysts (LEC...
By Carsten W. Israel and S. Serge Barold, eds. Armonk, NY: Futura Publishing Company,...
Third-degree AV block (3DAVB) of a persistent and not potentially reversible type ass...
Study objective: Noninvasive ventilation has been shown to be effective in patients w...
Study objectives: We described the features seen on serial high-resolution CT scans o...
Objective: To compare the results of pleural fluid analysis for WBC counts and differ...
Key words: asthma therapy; cyclosporine; drug therapy; furosemide; gold; heparin; IVI...
Our aim in the study was to investigate the pathogenesis of eosinophilic inflammation...
Fat embolism develops in nearly all patients with bone fractures or during orthopedic...
Objectives: Though numerous studies have demonstrated the short-term efficacy of lung...
Study objectives: Quadriceps fatigue can occur in patients with COPD after exhaustive...
Objective: To evaluate the effect of repeated thoracenteses on the fluid characterist...
Study objectives: Autopsy evaluation of tracheobronchomalacia (TBM) in patients with ...
Over the last years, many studies were aimed at better redefining the airway inflamma...
Study objectives: Supplemental oxygen is used in hypoxemic patients with chronic airw...
Study objectives: To evaluate the effect of interface on objective compliance, patien...
Objective: The aim of this article is to describe the high-resolution CT (HRCT) findi...
Background: Specific and nonspecific bronchial responsiveness may decline or disappea...
To the Editor: Varon et al (May 2002), (1) in an editorial accompanying the study o...
Study objective: The upper limbs are involved in the activities of daily living (ADLs...
Objectives: To compare and establish the relevance of the relative degree of sympathe...
Study objectives: To determine the impact of body mass index (BMI) on outcomes in cri...
A 49-year-old woman, who previously had been healthy with no significant comorbiditie...
Occupational asthma is not a rare disorder. Work-related asthma is now the most preva...
Study objectives: The relationship between smoking and COPD has been well-documented....
Study objectives: Home overnight pulse oximetry (OPO) is used to assess nocturnal des...
Study objective: To evaluate the clinical impact of nosocomial Enterobacter bacteremi...
Study objectives: The purpose of this study was to determine the reliability of two r...
Pulmonary arterial hypertension (PAH) is a serious, often fatal condition. The clinic...
Study objective: To study the role of orexins in regulating body composition in patie...
Background: Obstructive sleep apnea (OSA) is common in severely obese subjects (body ...
Study objectives: To determine if minute ventilation (VE) measured as a trend followi...
A 59-year-old man came to medical attention due to a heart murmur noted approximately...
The role of adenosine in mediating airway hyperreactivity is an interesting and emerg...
Study objectives: The objective of this study was to determine differences in airway ...
Study objectives: This study investigated to what extent a diagnosis of COPD is erron...
Study objective: To assess the clinical usefulness of blood cultures (BCs) in the man...
Study objectives: Despite the recognition that ventilator weaning is associated with ...
Objectives: To evaluate the effect of long-term oral therapy with sildenafil in patie...
Several years ago for this same journal, I wrote an editorial entitled "Asthma and Ga...
Study objective: To examine whether bronchial hyperresponsiveness (BHR) in patients w...
Study objectives: The physical and psychological effects of caregiving have been exam...
Study objective: Community-acquired pneumonia (CAP) accounts for an increasing propor...
Objective: To assess the applicability of the sequential organ failure assessment (SO...
We report a case of visceral larva migrans in an adult with fever, night sweats, weig...
We were delighted to review the article by Yusen et al in this issue of CHEST (see pa...
Background: Gastroesophageal reflux (GER) plays a role in inducing or exacerbating as...
Study objectives: The single-breath diffusing capacity of the lung (DLCO) is a common...
Study objectives: Neutrophilic inflammation is a major feature of COPD. Several facto...
The occurrence of pneumothorax after an invasive transthoracic procedure is a well-kn...
By Rade B. Vukmir. New York, NY: Parthenon Publishing Group, 2001; 136 pp; $64.95 A...
The human cough reflex is a vital protective and defensive reflex, and its integrity ...
Study objectives: To evaluate cough reflex sensitivity in a population of young, heal...
Study objectives: To document the existence and investigate the etiology of "thunders...
Objective: To identify potential prognostic factors for pulmonary thromboembolism (PT...
Study objective: To determine the effect of the addition of heliox to standard medica...
We report on the case of a 40-year-old patient with coagulopathic alcoholic cirrhosis...
Abbreviations: DX = dexamethasone; IL = interleukin Airway remodeling in asthma pat...
Both histamine and the leukotrienes are thought to be pivotal mediators in asthma as ...
Abbreviation: VASP = vasodilator-stimulated phosphoprotein The attachment and migra...
Abbreviations: ACTH = corticotropin; NA = nocturnal asthma; NL = control subject; NNA...
Abbreviation: LT[C.sub.4] = leukotriene [C.sub.4] The goal of this investigation wa...
The goal of this study was to determine whether sensations of dyspnea would change wh...
Asthma is at a crossroads. Although the clinical syndrome of asthma has been recogniz...
Treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) ...
Study objectives: The effectiveness of nasal continuous positive airway pressure (CPA...
Study objective: Exhaled nitric oxide (NO) levels are significantly elevated in patie...
Study objectives: To determine if intrapleural administration of methylprednisolone a...
In the February 2002 article, "A Cross-Cultural Comparison of Critical Care Delivery:...
Abbreviation: ASM = airway smooth muscle Over the last decade, there has been incre...
Abbreviations: E-IS = early induced-sputum collection; IS = induced sputum; L-IS = la...
Giles F. Filley Lecture Abbreviations: epi-vir-all = epithelial, viral, and allergi...
Severe asthma is poorly understood clinically, physiologically, and pathologically. W...
Abbreviation: SP = surfactant protein Mycoplasma pneumoniae can exacerbate asthma, ...
Trees in the birch family, including alder, hazel, and birch, have wind-pollinated fl...
In the 18th century, Albrecht von Haller (1) made the initial observation that the be...
Background: Diagnosis of obstructive sleep apnea syndrome (OSAS) by ambulatory system...
Study objective: Previous studies have suggested that aggressive treatment of sinusit...
Objectives: To assess the ability of selective bronchography to predict which patient...
Objective: Multivariable modeling techniques are appearing in today's medical literat...
Abbreviations: PV = pressure-volume; tPA = tissue plasminogen activator Airway fibr...
Abbreviation: ECP = eosinophil cationic protein Eosinophilic infiltration is a prom...
Abbreviations: EGF = epidermal growth factor; EGFR = epidermal growth factor receptor...
Abbreviations: OVA = ovalbumin; RW = ragweed; SIN = single intranasal challenge; TNF ...
Abbreviations: BHR = bronchial hyperresponsiveness; MP = Mycoplasma pneumoniae; PCR =...
Abbreviations: COX = cyclooxygenase; cPL[A.sub.2] = cytosolic phospholipase [A.sub.2]...
Pulmonologists routinely use pulmonary function tests (PFTs) to help guide their care...
Background: Determination of the therapeutic pressure during continuous positive airw...
Study objectives: To describe asthma features in a cohort with [[alpha].sub.1]-antitr...
Study objectives: To describe the variation in clinical practice strategies for the t...
A 10-year-old boy developed severe dyspnea and respiratory failure during a hospitali...
Abbreviations: DI = deep lung inflation; R = real part of impedance; Z = impedance ...
Abbreviations: HBEC =human bronchial epithelial cell; HFL = human fetal lung; GAPDH =...
Abbreviation: TER = transepithelial resistance During the immediate airway response...
Airway hyperresponsiveness is a characteristic feature of asthma and consists of an i...
Abbreviations: IL = interleukin; MMP = matrix metalloproteinase; TGF = transforming g...
Abbreviation: HDM = house dust mite Indoor allergens such as house dust mite (HDM) ...
May we say this in a prominent medical journal such as CHEST? Is it audacity or truth...
Study objective: To determine the validity of the association between systemic hypert...
Study objectives: To compare the safety and efficacy of oral azithromycin and levoflo...
Study objectives: To investigate the long-term outcome of lung function in survivors ...
A 36-year-old woman presents with dry cough and dyspnea on exertion, which have progr...
The 45th Annual Thomas L. Petty Aspen Lung Conference was held June 5 to 8, 2002. The...
Allergic diseases are most likely due to interactions between genetic and environment...
Lesions of the airway epithelium are frequently observed in asthma patients. Therefor...
Thomas A. Neff Lecture Respiratory tract infections caused by viruses, Chlamydia, a...
Abbreviations: AHR = airway hyperresponsiveness; ICAM = intercellular adhesion molecu...
The subepithelial thickening of asthmatic airways is manifested by increased fibrobla...
Abbreviations: IL = interleukin; NHLBI = National Heart, Lung, and Blood Institute; P...
Pneumonia occurring during mechanical ventilation, the so-called ventilator-associate...
Objectives: Patients with heart failure have increased circulating levels of tumor ne...
Study objectives: Neutrophilic inflammation is a major feature of COPD. Induced sputu...
Study objective: To determine the sensitivity, specificity, and positive and negative...
A 52-year-old male smoker presented with a 1-week history of fever, left-sided pleuri...
To the Editor: Integrity is the currency of scientific discourse; mendacity and att...
Interleukin (IL)-13 is a key cytokine in asthma pathogenesis. We used constitutive an...
Abbreviation: HASM = human airway smooth muscle We examined the ability of the cort...
Abbreviation: IL = interleukin The cellular events underlying the development and m...
Abbreviations: BHR = bronchial hyperresponsiveness; IFN = interferon; IL = interleuki...
Abbreviations: PDGF = platelet-derived growth factor; PDGFR = platelet-derived growth...
Abbreviation: RR = relative risk Genomic scans have identified a strong linkage of ...
Helium is an inert, colorless gas. It was discovered by spectroscopic methods during ...
Study objectives: Because muscle paralysis makes it uncertain whether subjects with s...
Pulmonary arteriovenous malformations (PAVMs) represent a direct communication betwee...
Study objectives: Pulmonary arteriovenous malformations (PAVMs) in patients with here...
Study objective: To evaluate the efficacy of a continuous thoracic paravertebral infu...
Background: Glucocorticoid treatment alters immunoregulatory defense mechanisms and m...
Pulmonary involvement is common in patients with portal hypertension and can manifest...
Study objective: Pulmonary lymphangioleiomyomatosis (LAM) is a rare, serious disorder...
In 1907, Pembrey (1) showed that supplemental nasal oxygen improved Cheyne-Stokes res...
Study objectives: The purpose of this study was to assess the clinical follow-up of a...
Background: Streptokinase is widely used IV for the treatment of myocardial infarctio...
Background: Whether clinicians should decrease the warfarin dose in response to a mil...
Intensivists are confronted with poisoned patients on a routine basis, with clinical ...
We report the case of a 51-year-old woman with a large cell bronchial carcinoma with ...
Originally timed walk/run tests (such as the 12-min running or walking test) have bee...
Aims: To evaluate the effects of mild hyperoxia on sympathetic activity during quiet ...
Study objective: To assess the value of chest ultrasonography vs clinical examination...
Study objective: To identify outcome predictors and prognostic factors in long-term s...
Key words: asthma, inhaled corticosteroids, long-acting [beta]-agonist, leukotriene r...
Pulmonary eosinophilia is an uncommon problem in lung transplant recipients. We repor...
If you save someone's life, you are responsible for them forever. This ancient Chin...
Background: Although nocturnal Cheyne-Stokes respiration alternating between hyperpne...
Purpose: A prospective comparison of three imaging techniques: thoracic CT, positron ...
Study objectives: To determine the prevalence of self-reported, heroin-associated ast...
Study objectives: It has been suggested that chronic viral infection may increase the...
Some diseases are inherently more difficult to diagnose with certainty than others. M...
Objectives: To assess the efficacy of medication for the treatment of pure coronary s...
Study objectives: To determine how frequently patients attending a lung cancer clinic...
Study objectives: To assess the cutoff percentage of cells containing intracellular o...
Study objectives: Several reports have suggested that subsets of asthmatic patients w...
The literature on diffuse alveolar hemorrhage heavily emphasizes the causal role of v...
This new 2003 version of the comprehensive electronic textbook of sleep medicine is a...
In this issue of CHEST (see page 436), Diacon et al report that bedside ultrasonograp...
Objectives: To determine the correlates of the total 6-min walk distance (6MWD) in a ...
Objective: A frequent problem in patients with intrathoracic malignancies neighboring...
Background: We recently reported that airway hyperresponsiveness (AHR) induced by a 6...
Study objectives: Conventional transbronchial needle aspiration (TBNA) is a valuable ...
We report a case of a 42-year-old man who fell in a vat of hydrochloric acid, resulti...
The pulmonologist is the focal point for the diagnosis and staging of lung cancer. Ac...
Background: The postthrombotic syndrome (PTS) occurs frequently after deep venous thr...
Background: Preoperative lymph node staging of lung cancer by CT relies on the premis...
Study objective: To test the hypothesis that exposure to hyperoxia during the postnat...
A 56-year-old woman presented with fever and productive cough of 2 weeks in duration....
Rationale: Although there have been reports of pulmonary toxicity with low-dose amiod...
There is no doubt that the best diagnostic strategy in patients with suspected ventil...
Purpose: To examine the time from the first physician visit to the diagnosis of sarco...
Study objectives: Diagnosis and medical intervention for exercise-induced bronchospas...
Study objective: Accumulation of somatic mutations of mitochondrial DNA (mtDNA) contr...
A 74-year-old woman presented to the operating room for drainage of an L3-4 abscess. ...
Objectives: The continuous IV administration of prostacyclin improves pulmonary hemod...
Study objective: To determine if cell wall-deficient forms (CWDF) of mycobacteria can...
Study objectives: Smoke inhalation has a prolonged, negative effect on pulmonary func...
Background: We recently developed a novel system for detecting microsatellite alterat...
A 64-year-old man presents with 2 months of intermittent blood-tinged sputum and coug...
Despite major advances in the medical treatment of chronic pulmonary artery hypertens...
Study objectives: The goal of this study was to determine whether the survival of pat...
Study objectives: The objectives of this study are as follows: (1) to determine the i...
Objective: To determine the utility of inhaled hypertonic saline solution to treat in...
Despite many years of clinical research, there is still no effective therapy for mali...
Background: While isolating the pulmonary arterial branches within the fissure is a c...
After the identification of the cystic fibrosis (CF) gene in 1989 (1) and the emergen...
Study objective: Lung transplantation is now available for patients with cystic fibro...
Setting: Seven primary health clinics and a pulmonary disease specialty clinic in Rio...
Study objectives: To determine whether the nuclear accumulation of p53 in patients wi...
Study objectives: To assess the impact of a proactive case finding approach to end-of...
Lung cancer involvement of the heart is silent, carries a poor prognosis, and is most...
This chapter describes the components of the initial evaluation for a patient either ...
Based on clinical assessment alone, patients with stage II non-small cell lung cancer...
Many of the "dogmas of the quiet past" (1) have given way to more well-founded concep...
Study objectives: The development and psychometric properties of an additional diseas...
Study objectives: To determine the intracellular and extracellular Mg concentrations ...
Introduction: We have demonstrated that a component of post-cardiopulmonary bypass (C...
A 27-year-old woman from Trinidad presented at a rehabilitation facility with a 3-day...
The numbers are staggering. It is projected that 169,400 individuals in the United St...
The preoperative physiologic assessment of a patient being considered for surgical re...
Stage IIIa non-small cell lung cancer represents a relatively heterogeneous group of ...